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Publications

Publications:

Find all publications here.

Selected publications:

Groh S, Schotta G. Silencing of endogenous retroviruses by heterochromatin.
Cell Mol Life Sci. 2017 Jun;74(11):2055-2065.

Ramesh V, Bayam E, Cernilogar FM, Bonapace IM, Schulze M, Riemenschneider MJ,
Schotta G, Götz M. Loss of Uhrf1 in neural stem cells leads to activation of
retroviral elements and delayed neurodegeneration. Genes Dev. 2016 Oct
1;30(19):2199-2212.

Pasquarella A, Ebert A, Pereira de Almeida G, Hinterberger M, Kazerani M,
Nuber A, Ellwart J, Klein L, Busslinger M, Schotta G. Retrotransposon
derepression leads to activation of the unfolded protein response and apoptosis
in pro-B cells. Development. 2016 May 15;143(10):1788-99.

Sadic D, Schmidt K, Groh S, Kondofersky I, Ellwart J, Fuchs C, Theis FJ,
Schotta G. Atrx promotes heterochromatin formation at retrotransposons. EMBO Rep.
2015 Jul;16(7):836-50.

Recent publications:

Garg G, Muschaweckh A, Moreno H, Vasanthakumar A, Floess S, Lepennetier G,
Oellinger R, Zhan Y, Regen T, Hiltensperger M, Peter C, Aly L, Knier B, Palam LR,
Kapur R, Kaplan MH, Waisman A, Rad R, Schotta G, Huehn J, Kallies A, Korn T.
Blimp1 Prevents Methylation of Foxp3 and Loss of Regulatory T Cell Identity at
Sites of Inflammation. Cell Rep. 2019 Feb 12;26(7):1854-1868.e5.

Di Giaimo R, Durovic T, Barquin P, Kociaj A, Lepko T, Aschenbroich S, Breunig
CT, Irmler M, Cernilogar FM, Schotta G, Barbosa JS, Trümbach D, Baumgart EV,
Neuner AM, Beckers J, Wurst W, Stricker SH, Ninkovic J. The Aryl Hydrocarbon
Receptor Pathway Defines the Time Frame for Restorative Neurogenesis. Cell Rep.
2018 Dec 18;25(12):3241-3251.e5.

Wang X, Sterr M, Burtscher I, Chen S, Hieronimus A, Machicao F, Staiger H,
Häring HU, Lederer G, Meitinger T, Cernilogar FM, Schotta G, Irmler M, Beckers J,
Hrabě de Angelis M, Ray M, Wright CVE, Bakhti M, Lickert H. Genome-wide analysis
of PDX1 target genes in human pancreatic progenitors. Mol Metab. 2018
Mar;9:57-68.

Bosch-Presegué L, Raurell-Vila H, Thackray JK, González J, Casal C,
Kane-Goldsmith N, Vizoso M, Brown JP, Gómez A, Ausió J, Zimmermann T, Esteller M,
Schotta G, Singh PB, Serrano L, Vaquero A. Mammalian HP1 Isoforms Have Specific
Roles in Heterochromatin Structure and Organization. Cell Rep. 2017 Nov
21;21(8):2048-2057.

Brustel J, Kirstein N, Izard F, Grimaud C, Prorok P, Cayrou C, Schotta G,
Abdelsamie AF, Déjardin J, Méchali M, Baldacci G, Sardet C, Cadoret JC, Schepers
A, Julien E. Histone H4K20 tri-methylation at late-firing origins ensures timely
heterochromatin replication. EMBO J. 2017 Sep 15;36(18):2726-2741.

Groh S, Schotta G. Silencing of endogenous retroviruses by heterochromatin.
Cell Mol Life Sci. 2017 Jun;74(11):2055-2065.

Bromberg KD, Mitchell TR, Upadhyay AK, Jakob CG, Jhala MA, Comess KM, Lasko
LM, Li C, Tuzon CT, Dai Y, Li F, Eram MS, Nuber A, Soni NB, Manaves V, Algire MA,
Sweis RF, Torrent M, Schotta G, Sun C, Michaelides MR, Shoemaker AR, Arrowsmith
CH, Brown PJ, Santhakumar V, Martin A, Rice JC, Chiang GG, Vedadi M,
Barsyte-Lovejoy D, Pappano WN. The SUV4-20 inhibitor A-196 verifies a role for
epigenetics in genomic integrity. Nat Chem Biol. 2017 Mar;13(3):317-324.

Ramesh V, Bayam E, Cernilogar FM, Bonapace IM, Schulze M, Riemenschneider MJ,
Schotta G, Götz M. Loss of Uhrf1 in neural stem cells leads to activation of
retroviral elements and delayed neurodegeneration. Genes Dev. 2016 Oct
1;30(19):2199-2212.

Guida V, Cernilogar FM, Filograna A, De Gregorio R, Ishizu H, Siomi MC,
Schotta G, Bellenchi GC, Andrenacci D. Production of Small Noncoding RNAs from
the flamenco Locus Is Regulated by the gypsy Retrotransposon of Drosophila
melanogaster. Genetics. 2016 Oct;204(2):631-644.

Nelson DM, Jaber-Hijazi F, Cole JJ, Robertson NA, Pawlikowski JS, Norris KT,
Criscione SW, Pchelintsev NA, Piscitello D, Stong N, Rai TS, McBryan T, Otte GL,
Nixon C, Clark W, Riethman H, Wu H, Schotta G, Garcia BA, Neretti N, Baird DM,
Berger SL, Adams PD. Mapping H4K20me3 onto the chromatin landscape of senescent
cells indicates a function in control of cell senescence and tumor suppression
through preservation of genetic and epigenetic stability. Genome Biol. 2016 Jul
25;17(1):158.

Rhodes CT, Sandstrom RS, Huang SA, Wang Y, Schotta G, Berger MS, Lin CA.
Cross-species Analyses Unravel the Complexity of H3K27me3 and H4K20me3 in the
Context of Neural Stem Progenitor Cells. Neuroepigenetics. 2016 Jun;6:10-25.

Rocha PP, Raviram R, Fu Y, Kim J, Luo VM, Aljoufi A, Swanzey E, Pasquarella
A, Balestrini A, Miraldi ER, Bonneau R, Petrini J, Schotta G, Skok JA. A
Damage-Independent Role for 53BP1 that Impacts Break Order and Igh Architecture
during Class Switch Recombination. Cell Rep. 2016 Jun 28;16(1):48-55.

Eck S, Wörz S, Müller-Ott K, Hahn M, Biesdorf A, Schotta G, Rippe K, Rohr K.
A spherical harmonics intensity model for 3D segmentation and 3D shape analysis
of heterochromatin foci. Med Image Anal. 2016 Aug;32:18-31.

Pasquarella A, Ebert A, Pereira de Almeida G, Hinterberger M, Kazerani M,
Nuber A, Ellwart J, Klein L, Busslinger M, Schotta G. Retrotransposon
derepression leads to activation of the unfolded protein response and apoptosis
in pro-B cells. Development. 2016 May 15;143(10):1788-99.

Wang Y, Rank G, Li Z, Wang Y, Ju J, Nuber A, Wu Y, Liu M, Nie M, Huang F,
Cerruti L, Ma C, Tan R, Schotta G, Jane SM, Zeng CK, Zhao Q. ε-globin expression
is regulated by SUV4-20h1. Haematologica. 2016 May;101(5):e168-72. doi:
10.3324/haematol.2015.139980.

Sadic D, Schmidt K, Groh S, Kondofersky I, Ellwart J, Fuchs C, Theis FJ,
Schotta G. Atrx promotes heterochromatin formation at retrotransposons. EMBO Rep.
2015 Jul;16(7):836-50.